HPMC Capsules — QUALI-V®-N

Health food capsules

HPMC Capsules

HPMC Capsules — QUALI-V®-N

Plant-derived hydroxypropyl methylcellulose (HPMC) -based capsules,
developed by Qualicaps®.

HPMC Capsules — QUALI-V®-N

Product Overview

  • Hydroxypropyl methylcellulose (HPMC) is 100% plant-based and QUALI-V®-N includes no animal-sourced raw materials whatsoever.
  • Chemically stable and unaffected by drug contents.
  • Less affected by mechanical strength by air humidity and suitable for hygroscopic APIs.
  • The Japanese Institute for Health Food Standards (JIHFS)-GMP certification is obtained and QUALI-V® capsules are manufactured in a validated production environment.
  • Free of preservative and allergen (28 raw materials identified as allergens in Japan).
  • It is possible to fill with a combination of two or more types of preparations, such as solid, oily liquid, and semi-solid preparations (oily liquid and semi-solid preparations need the band sealing).

QUALI-V®-N capsules are ideal for the following substances.

  1. Substances that may become very unstable due to moisture: Vitamins such as Vitamin C and any of the B group, heme iron
  2. Substances made from natural extracts that are highly hygroscopic: natural remedies, natural herbs, fermentation extracts
  3. Substances with components that are prone to react with gelatin: Vitamin C, DHA/EPA (fish oils)

Color Lineup

The following capsule colors are available in our standard lineup.

  • WhiteWhite
  • ClearClear
  • Clear Dark CaramelClear Dark Caramel
  • Clear Light CaramelClear Light Caramel
  • Clear GreenClear Green

Please contact us for inquiries about capsule stock and other colors.

Capsule Printing

Two imprinting methods are available:
・Offset printing with two color ink
・UV lazer printing with no ink : Qualicaps®'s own technology

Offset printing

Offset printing uses edible ink,
in which two colors, white and black, are available.

Offset printing
UV lazer printing

UV lazer printing technology utilizes the color change of titanium oxide by UV irradiation.
UV lazer can print fine design to capsules.

UV lazer printing

Capsule Sizes

Available in 4 sizes, from 0 to 3.

In addition, please contact us for inquiries about the special size.

Capsule Sizes
Size (♯) 0 1 2 3
Volume (mL) 0.68 0.49 0.37 0.28

Packaging Quantities (number included)

The standard numbers of capsules packed in each case for outside of Japan are as follows.

Capsule size (♯) Standard quantities
0 90,000
1 Transparent capsules 100,000
Opaque capsules 125,000
2 150,000
3 200,000

Test Data

Dissolution Test

The dissolution property of QUALI-V®-N capsules is almost the same in different dissolution media: water, 1st fluid for dissolution test (simulating gastric fluid),
2nd fluid for dissolution test (simulating intestinal fluid).

Test Data
n=6
Source: In-house data
Test conditions

Capsule size: ♯3

Apparatus: Paddle method, 50 rpm, UV detection

Dissolution media: water, 1st fluid for dissolution test, or 2nd fluid for dissolution test, 900 mL each

Capsule fill formulation: 20% acetaminophen mixture

Fill weight: 200 mg

Documentation

We prepare accreditations and/or certifications for QUALI-V®-N. For further reference, please contact us for further information.

JIHFS-GMP Certification (Copy) Kosher Certification (Copy)
GMO Statement Allergen Statement Titanium Oxide Statement
Gluten Statement Agricultural Chemical Residues in Foods Statement Food Utensils, Containers, and Packaging Statement
Irradiation Statement
SDS Capsule Specifications Flow of Manufacturing Capsules
Test Methods Capsule Theoretical Formula COA Sample

Additionally, Qualicaps® received ISO9001 and ISO14001 certification.
See ″ISO Management″ for further details.

Related Products

Trademark

QUALI-V is a registered trademark of Qualicaps in China, India, US, Canada, EU, Swiss, and UK.

Inquiries / Downloads

For inquiries about capsules or equipment, or to download reference materials, click on the links below.