Hydroxypropyl methylcellulose (HPMC) is 100% plant-based and QUALI-V®-N includes no animal-sourced raw materials whatsoever.
Chemically stable and unaffected by drug contents.
Less affected by mechanical strength by air humidity and suitable for hygroscopic APIs.
Free of allergen (28 raw materials identified as allergens in Japan).
It is possible to fill with a combination of two or more types of preparations, such as solid, oily liquid, and semi-solid preparations (oily liquid and semi-solid preparations need the band sealing).
QUALI-V®-N capsules are ideal for the following substances.
Substances that may become very unstable due to moisture: Vitamins such as Vitamin C and any of the B group, heme iron
Substances made from natural extracts that are highly hygroscopic: natural remedies, natural herbs, fermentation extracts
Substances with components that are prone to react with gelatin: Vitamin C, DHA/EPA (fish oils)
Color Lineup
The following capsule colors are available in our standard lineup.
White
Clear
Clear Dark Caramel
Clear Green
Please contact us for inquiries about capsule stock.
Capsule Sizes
Available in 3 sizes, from 1 to 3.
Size (♯)
1
2
3
Volume (mL)
0.49
0.37
0.28
Packaging Quantities (number included)
The standard numbers of capsules packed in each case for outside of Japan are as follows.
Capsule size (♯)
Standard quantities
1
Transparent capsules
100,000
Opaque capsules
125,000
2
150,000
3
200,000
Test Data
Dissolution Test
The dissolution property of QUALI-V®-N capsules is almost the same in different dissolution media: water, 1st fluid for dissolution test (simulating gastric fluid), 2nd fluid for dissolution test (simulating intestinal fluid).
Test conditions
Capsule size: ♯3
Apparatus: Paddle method, 50 rpm, UV detection
Dissolution media: water, 1st fluid for dissolution test, or 2nd fluid for dissolution test, 900 mL each
Capsule fill formulation: 20% acetaminophen mixture
Fill weight: 150 mg
Documentation
We prepare accreditations and/or certifications for QUALI-V®-N. For further reference, please contact us for further information.
Kosher Certification (Copy)
GMO Statement
Allergen Statement
Titanium Oxide Statement
Agricultural Chemical Residues in Foods Statement
Food Utensils, Containers, and Packaging Statement